Pasar al contenido principal

Studies on heat stress in dairy cattle and pigs.

Enviado por Anónimo (no verificado) el
default

Under heat stress, production decreases, fertility decreases even more, and animals have a decreased chance of survival (St. Pierre et al., 2003). Heat stress can be mitigated in two ways:by environmental management, such as cooling devices or timing of reproduction West, 2003), or by genetic selection (Misztal et al., 2002). Heat stress in farm animals is likely to become a bigger problem due to global warming.

Single-step genomic BLUP for national beef cattle evaluation in US:from initial developments to final implementation.

Enviado por Anónimo (no verificado) el
default

ABSTRACT. The objective of this study was to implement single-step genomic BLUP (ssGBLUP) for national Angus cattle evaluation in the US. National evaluations include a variety of models with several linear and categorical traits, maternal effects, multibreed data, and a large number of genotyped animals. For the initial investigation, we used a dataset from 2014 that comprised over 8 million animals, 6 million birth weight (BW) and weaning weight (WW) records, 3.4 million post-weaning gain (PWG) records, and genotypes for 52k animals.

Single-step genomic BLUP for national beef cattle evaluation in US: from initial developments to final implementation.

Enviado por Anónimo (no verificado) el
default

ABSTRACT. The objective of this study was to implement single-step genomic BLUP (ssGBLUP) for national Angus cattle evaluation in the US. National evaluations include a variety of models with several linear and categorical traits, maternal effects, multibreed data, and a large number of genotyped animals. For the initial investigation, we used a dataset from 2014 that comprised over 8 million animals, 6 million birth weight (BW) and weaning weight (WW) records, 3.4 million post-weaning gain (PWG) records, and genotypes for 52k animals.

Genetic parameters for body weight, worm resistance, packed cell volume and FAMACHA@ under natural infection in Corriedale sheep.

Enviado por Anónimo (no verificado) el
default

ABSTRACT. Gastrointestinal parasites (GIP) are one of the main constraint for sheep production worldwide. In Uruguay, the most prevalent and pathogenic parasite is Haemonchus contortus. One approach to control parasite infection is to select genetically resistant animals into a sheep-breeding program. Faecal egg count (FEC) is the criterion most used to evaluate genetic resistance to GIP, although there are alternative indicators that could be used.

Across-breeds ancestral relationships and metafounders for genomic evaluation.

Enviado por Anónimo (no verificado) el
default

ABSTRACT. A theory to account for across-founder ancestral relationships is presented, which can consider relationships within and across populations. The theory assumes finite size of the ancestral population. Ancestral relationships can be represented as metafounders, pseudo-individuals that can be seen as pool of gametes and as extensions of random genetic groups. Simple rules exist for computation of relationships, inbreeding, and the inverse of the relationship matrix. Values of the Ancestral relationships can be inferred from marker relationships and pedigrees.

Quality control of genotypes using heritability estimates of gene content.

Enviado por Anónimo (no verificado) el
default

ABSTRACT. Quality control filtering of single nucleotide polymorphisms (SNP) is a key step when analyzing genomic data. Here, we present a practical method to identify poorly genotyped SNPs by detecting those for which gene content deviates from the pedigree-based expectation. This can be achieved by estimating the heritability of gene content at each marker, defined as the number of copies of a particular reference allele in a genotype of an animal (0, 1 or 2).

PREGSF90 - POSTGSF90:Computational tools for the implementation of single-step genomic selection and genome-wide association with ungenotyped individuals in BLUPF90 programs.

Enviado por Anónimo (no verificado) el
default

ABSTRACT. Single step genomic methodology provides a unified framework to integrate phenotypic, pedigree and genomic information in prediction of breeding values for all individuals and in estimation of marker effects. Computational tools for the implementation of the single-step methodology are presented. Methodology, quality control of samples and different options to create genomic relationship matrices are discussed.

PREGSF90 - POSTGSF90: Computational tools for the implementation of single-step genomic selection and genome-wide association with ungenotyped individuals in BLUPF90 programs.

Enviado por Anónimo (no verificado) el
default

ABSTRACT. Single step genomic methodology provides a unified framework to integrate phenotypic, pedigree and genomic information in prediction of breeding values for all individuals and in estimation of marker effects. Computational tools for the implementation of the single-step methodology are presented. Methodology, quality control of samples and different options to create genomic relationship matrices are discussed.